Matt Sakiyama
Alkes Price Group at Harvard School of Public Health
- Worked under guidance of Prof. Alkes Price
- Wrote scripts in Python to estimate heritability of diseases cataloged in UK Biobank database
- Quantified heritability contributions from genetic signals using regression scoring
- Summarized and presented research on genetic fine mapping techniques and heritability estimation
Christopher Burge Laboratory at MIT
- Worked under guidance of Dr. Scott Findlay, PhD
- Wrote scripts in R to process and plot large string data to identify alternative polyadenylation sites
- Collated and filtered annotations across UCSC genome browser, GENCODE and polyA_DB datasets
- Summarized research on 3’ untranslated regions and applications of alternative polyadenylation sites
- Presented work in weekly meetings
Molecular Biology Research
- Co-lead of research team
- Conducted original research on dopamine signalling in C. elegans in partnership with Stanford Shen Lab
- Planned to present data at annual meeting of the American Society for Biochemistry and Molecular Biology before cancellation due to COVID-19
- Performed PCR, gel electrophoresis, and nematode husbandry
- Analyzed video data using WormLab
- Performed lab procedures using autoclave, vortex, centrifuge, micropipette
- Teach basic lab skills and provide guidance to new research program members
Invention Studio
- Co-founder and co-lead of Team MODAP
- Design and prototype affordable drones for California firefighters’ search and rescue operations
- Collect feedback from potential users about concept of operations
- Lead weekly meetings and recruit and train new members
- Manage competition applications and team tasks
- Received a $3500 grant from the Joey Kovacevich Social Innovation Fellowship
- Placed as Finalist in 2020 Diamond Challenge
- Planned to present at 2020 SXSW Education Conference Student Startup Competition before cancellation due to COVID-19
- MODAP website
Eisai Pharmaceuticals: Genetics Guided Dementia Discovery Internship
- Studied DNA extraction, microscopy, and data analysis under the Founder and President of the Center for Genetics Guided Dementia Discovery
- Investigated the recent worldwide increase in Alzheimer’s Disease cases
- Led a team of students from across the nation in developing a product to combat the negative effects of the COVID-19 pandemic on Alzheimer’s patients
Pendulum Clock
- Designed and components of the escapement mechanism using Fusion360
- Prototyped pendulum clock components using various tools, including laser cutter and 3-D printer
- Assembled functioning pendulum escapement mechanism
Project 80
- Research commonly debated topics of scientific interest
- Record and edit audio for podcasts
- Release podcasts to whole-school community with the aim of educating 80% of community and encouraging data-driven thinking
- Most recent podcast